Vitamin D composition data for Australian foods - Lucinda Black
This project aims to quantify the dietary supply of vitamin D in Australia by analysing its content in food using innovative methodology recently developed in Australia. Despite widespread vitamin D deficiency, the contribution of diet to vitamin D status is unknown. The intended outcomes of this project are to produce vitamin D composition data to inform public health policies, provide the first estimate of vitamin D intake in both the general Australian population and the Aboriginal and Torres Strait Islander population, and develop high quality scientific outputs. Australian vitamin D composition data will be of benefit both nationally and internationally, since limited composition data exist using this unique analytical methodology.
Sunlight, nitric oxide and obesity: investigating mechanisms by which ultraviolet radiation suppresses signs of obesity and metabolic dysfunction
Obesity is a crucial health and economic problem for Australians. In recent studies, we have found that frequent skin exposure to a low non-burning dose of ultraviolet radiation reduced weight gain in mice fed a high fat diet. These findings were independent of circulating vitamin D, and could not be mimicked by vitamin D supplementation. We are now starting to characterise the biological mediators (like nitric oxide) affected by ultraviolet irradiation and their potential to prevent obesity. Our novel findings suggest that ongoing exposure to safe doses of sunlight may prevent the development of obesity and metabolic dysfunction.
Vitamin D status and the relationship with cardiometabolic risk factors in a Western Australian adolescent population - Trevor Mori
Using prospective data from the Western Australian Pregnancy Cohort (Raine) Study we investigated vitamin D status, predictors of serum 25-hydroxyvitamin D (25(OH)D) concentrations and cardiometabolic risk factors in adolescents and young adults. At 14 and 17 years 4% and 12%, respectively had serum 25(OH)D <50 nmol/l. Caucasian ethnicity, being sampled at the end of summer, exercising more, having a lower BMI, a higher calcium intake and a higher family income were signiﬁcantly associated with higher serum 25(OH)D concentrations. Hierarchical linear mixed models with maximum likelihood estimation were used to investigate associations between vitamin D at 17 and 20 years and cardiovascular risk factors. Serum 25(OH)D was inversely associated with BMI and insulin resistance, and in girls it was positively associated with triglycerides. There were no significant associations between serum 25(OH)D and high-density lipoprotein-cholesterol or systolic blood pressure.